cat ./research.md
● three themes
Research themes.
Our main topics involve
./Themes
01 / exposures
Integrative multi-omics of environmental exposures.
Environmental exposures contribute substantially to interindividual variation in health and disease.
We use integrative multi-omics approaches to characterize how diverse exposures are biologically embedded across molecular layers, with particular attention to sex-specific effects.
Our work aims to generate mechanistic hypotheses linking exposure profiles to downstream biological pathways, including projects on tobacco smoke, occupational exposures, and other environmental stressors.
Environmental exposures contribute substantially to interindividual variation in health and disease.
We use integrative multi-omics approaches to characterize how diverse exposures are biologically embedded across molecular layers, with particular attention to sex-specific effects.
Our work aims to generate mechanistic hypotheses linking exposure profiles to downstream biological pathways, including projects on tobacco smoke, occupational exposures, and other environmental stressors.
02 / sex differences
Multi-omics characterization of sex differences in neurodegenerative disease.
Sex differences are a major source of heterogeneity in neurodegenerative disorders, including Alzheimer's disease, yet their molecular bases remain poorly resolved.
We apply integrative multi-omics analyses to identify sex-specific molecular signatures associated with disease risk, progression, and phenotypic variation.
This work emphasizes mechanistic insight across molecular, clinical, and cognitive levels.
Sex differences are a major source of heterogeneity in neurodegenerative disorders, including Alzheimer's disease, yet their molecular bases remain poorly resolved.
We apply integrative multi-omics analyses to identify sex-specific molecular signatures associated with disease risk, progression, and phenotypic variation.
This work emphasizes mechanistic insight across molecular, clinical, and cognitive levels.
03 / society
Cross-cutting: Ethical and societal dimensions of integrative omics research.
The rapid expansion of multi-omics and integrative biomedical research raises important ethical, social, and epistemological questions.
We engage with these issues by examining how biological knowledge production intersects with environmental injustice, climate-related change, and social inequities.
This work draws on interdisciplinary bioethics perspectives to inform responsible and context-aware biomedical research.
The rapid expansion of multi-omics and integrative biomedical research raises important ethical, social, and epistemological questions.
We engage with these issues by examining how biological knowledge production intersects with environmental injustice, climate-related change, and social inequities.
This work draws on interdisciplinary bioethics perspectives to inform responsible and context-aware biomedical research.